Tmed10 atg4b
WebDeWalt / Delta Porter-Cable Factory Service #042. 3557-B WILKINSON Charlotte, NC 28208 USA. Telephone: 704-392-0245. Approximate distance: 5.1 miles. Support for Dewalt … WebSep 9, 2024 · TMED10:GFP is stained in green, GM130 in red and nucleus in blue. Dotted squares are magnified on the right, arrows show TMED10:GFP-only-labeled vesicles. n =3 independent experiments. Scale bars: 10 µm; 5 µm in zoom. (B) Quantification of TMED10 and GM130 colocalization.
Tmed10 atg4b
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WebMar 19, 2024 · The results suggest that the AD-associated protein TMED10 negatively regulates autophagy by inhibiting ATG4B activity. ABSTRACT Several studies have shown that dysfunction of macroautophagy/autophagy is associated with many human diseases, including neurodegenerative disease and cancer. To explore the molecular mechanisms … WebMar 1, 2024 · Several studies have shown that dysfunction of macroautophagy/autophagy is associated with many human diseases, including neurodegenerative disease and cancer. …
WebMarketplace is a convenient destination on Facebook to discover, buy and sell items with people in your community. WebMar 1, 2024 · Interestingly, protein-protein interaction assays showed that TMED10 directly binds to ATG4B (autophagy related gene 4B cysteine peptidase), and the interaction is diminished under autophagy activation conditions such as …
WebATG4B. In this study, we performed a detailed characterization of human cells lacking ATG4B to determine its role in autop-hagy. We show that loss of ATG4B causes severe defects in autophagy and LC3/GABARAP processing, however the remaining ATG4 activity is sufficient for residual lipidation and autophagosome localization of GABARAP subfamily ... WebApr 30, 2024 · In the cell, TMED10 localizes on the endoplasmic reticulum (ER)-Golgi intermediate compartment and directs the entry of cargoes into this compartment. Furthermore, cargo induces the formation of TMED10 homo-oligomers which may act as a protein channel for cargo translocation.
WebOct 26, 2024 · A previous study demonstrated that TMED10 directly interacts with ATG4B and suppresses the effect of ATG4B on LC3 cleavage and indicated that downregulation …
ba1 ba4/5 ワクチン どっちWebFigure Legend Snippet: Downregulation of TMED10 increases the proteolytic activity of ATG4B. ( A ) Schematic diagram of the quantification of ATG4B activity using an assay based on a luciferase-release system. ( B and C ) SH-SY5Y cells transfected with pEAK12-Actin-LC3-dNGLUC were transfected with scrambled siRNA ( Sc ) or TMED10 siRNA ( … ba1 ba4-5 ワクチン 違いWebGene "Gene description" Evidence A1CF "APOBEC1 complementation factor" "Evidence at protein level" A4GALT "Alpha 1,4-galactosyltransferase (P blood group)" "Evidence at protein le 千葉県 年末年始 バイトWebHome: Cell Press ba1 ba4/5 ワクチン 違いWebMar 29, 2024 · The AD-associated protein TMED10 negatively regulates autophagy by inhibiting ATG4B activity. Study validated EXT1, TM9SF2, and TMED10 as important host … 千葉県市町村職員共済組合 サポート保険とはWebMar 21, 2024 · TMED10 (Transmembrane P24 Trafficking Protein 10) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Golgi-to-ER retrograde transport . Gene Ontology (GO) annotations related to this gene include protein-containing complex binding and syntaxin binding . 千葉県 平屋 ローコストWebFurthermore, the interaction between TMED10 and ATG4B was also decreased under serum-free conditions (Figure 5(B)), suggesting that TMED10 may dissociate from ATG4B during … ba1 ba4/5 どっち